Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
| Upregulated in class | truncNotch |
| GeneSet | INOH_NOTCH SECRETORY PATHWAY |
| Enrichment Score (ES) | -0.7511448 |
| Normalized Enrichment Score (NES) | -1.4646055 |
| Nominal p-value | 0.033771105 |
| FDR q-value | 0.4518904 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MFNG | 1770242 4280348 | 472 | 0.786 | 0.0222 | No | ||
| 2 | ADAM17 | 360292 | 717 | 0.625 | 0.0469 | No | ||
| 3 | MAML1 | 2760008 | 876 | 0.553 | 0.0718 | No | ||
| 4 | CREBBP | 5690035 7040050 | 909 | 0.541 | 0.1028 | No | ||
| 5 | LFNG | 5360711 | 2316 | 0.154 | 0.0365 | No | ||
| 6 | ITCH | 1410731 5700022 | 2628 | 0.116 | 0.0268 | No | ||
| 7 | JAG2 | 1500341 | 3300 | 0.060 | -0.0057 | No | ||
| 8 | NUMB | 2450735 3800253 6350040 | 4025 | 0.028 | -0.0429 | No | ||
| 9 | NOTCH2 | 2570397 | 5426 | 0.009 | -0.1177 | No | ||
| 10 | DLL1 | 1770377 | 6187 | 0.005 | -0.1583 | No | ||
| 11 | ADAM10 | 3780156 | 7349 | 0.002 | -0.2206 | No | ||
| 12 | JAG1 | 3440390 | 8844 | -0.002 | -0.3008 | No | ||
| 13 | DLL3 | 4010093 | 9233 | -0.003 | -0.3215 | No | ||
| 14 | NOTCH4 | 2450040 6370707 | 11342 | -0.010 | -0.4343 | No | ||
| 15 | DLL4 | 6400403 | 12673 | -0.019 | -0.5046 | No | ||
| 16 | RBPJ | 2360164 5550136 5720402 | 14993 | -0.071 | -0.6251 | No | ||
| 17 | FURIN | 4120168 | 15079 | -0.076 | -0.6250 | No | ||
| 18 | FBXW7 | 4210338 7050280 | 15517 | -0.104 | -0.6422 | No | ||
| 19 | RFNG | 6290086 | 16509 | -0.229 | -0.6817 | No | ||
| 20 | DTX2 | 4210041 7000008 | 17801 | -0.534 | -0.7188 | Yes | ||
| 21 | PSEN2 | 130382 | 17846 | -0.558 | -0.6874 | Yes | ||
| 22 | DTX3 | 1690458 | 18348 | -1.048 | -0.6509 | Yes | ||
| 23 | NOTCH3 | 3060603 | 18544 | -2.010 | -0.5398 | Yes | ||
| 24 | NOTCH1 | 3390114 | 18550 | -2.087 | -0.4138 | Yes | ||
| 25 | PSEN1 | 130403 2030647 6100603 | 18581 | -2.626 | -0.2564 | Yes | ||
| 26 | DTX1 | 5900372 | 18604 | -4.268 | 0.0006 | Yes |
